Light Therapy for Fibromyalgia Relief: A Review of Photobiomodulation Research

Fibromyalgia is a chronic pain condition that affects millions of people worldwide, causing widespread pain, fatigue, and cognitive difficulties. Photobiomodulation, commonly known as light therapy, has shown promise in reducing pain and improving the quality of life for individuals with fibromyalgia. This article will explore the science behind light therapy for fibromyalgia and discuss five influential research papers that have shaped our understanding of its effectiveness.

How Light Therapy Supports Fibromyalgia Management

Light therapy uses specific wavelengths of light, typically in the red and near-infrared spectrum, to stimulate cellular processes within the body. When the skin absorbs light at these wavelengths, it triggers a series of events at the cellular level that enhance the body's natural healing processes. Key mechanisms involved in fibromyalgia management through light therapy include:

  1. Pain relief: Light therapy can modulate pain signals in the nervous system, leading to a reduction in perceived pain.
  2. Reduced inflammation: Light therapy can decrease the production of pro-inflammatory cytokines, thereby reducing inflammation and alleviating fibromyalgia symptoms.
  3. Improved blood circulation: Light therapy enhances blood flow and circulation, providing tissues with more oxygen and nutrients while removing waste products. This improved circulation supports overall well-being and symptom relief.
  4. Muscle relaxation: Light therapy can promote muscle relaxation, reducing muscle stiffness and tension commonly experienced in fibromyalgia patients.

Five Influential Research Papers on Light Therapy and Fibromyalgia

1. Armagan, O., Tascioglu, F., Ekim, A., & Oner, C. (2006). Long-term efficacy of low-level laser therapy in women with fibromyalgia: a placebo-controlled study. Journal of Back and Musculoskeletal Rehabilitation, 19(4), 135-140.

This placebo-controlled study investigated the long-term efficacy of low-level laser therapy in women with fibromyalgia. The results demonstrated that light therapy significantly reduced pain and improved functional status, suggesting the potential benefits of light therapy for fibromyalgia management.

2. Gür, A., Karakoc, M., Nas, K., Cevik, R., Saraç, J., & Demir, E. (2002). Effects of low power laser and low dose amitriptyline therapy on clinical symptoms and quality of life in fibromyalgia: a single-blind, placebo-controlled trial. Rheumatology International, 22(5), 188-193.

In this single-blind, placebo-controlled trial, the authors examined the effects of low-power laser therapy and low-dose amitriptyline therapy on clinical symptoms and quality of life in fibromyalgia patients. The study found that light therapy, combined with amitriptyline, significantly improved pain, fatigue, and quality of life.

3. Ruaro, J. A., Fréz, A. R., Ruaro, M. B., & Nicolau, R. A. (2014). Low-level laser therapy to treat fibromyalgia. Lasers in Medical Science, 29(6), 1815-1819.

This study investigated the effectiveness of low-level laser therapy in treating fibromyalgia. The results demonstrated significant improvements in pain, fatigue, and stiffness, supporting the use of light therapy as a potential treatment option for fibromyalgia.

4. de Carvalho, P. D. C., Leal-Junior, E. C. P., Alves, A. C. A., Rambo, C. S., Sampaio, L. M., Oliveira, C. S., ... & Bjordal, J. M. (2014). Effect of pre-irradiation with different doses, wavelengths, and application intervals of low-level laser therapy on cytochrome c oxidase activity in intact skeletal muscle of rats. Lasers in Medical Science, 29(1), 161-168.

Although this study focuses on the effect of low-level laser therapy on cytochrome c oxidase activity in rat skeletal muscle, it provides valuable insights into the mechanisms through which light therapy may alleviate fibromyalgia symptoms. By enhancing mitochondrial function, light therapy can promote cellular energy production and reduce muscle fatigue, which is a common symptom of fibromyalgia.

5. Matsutani, L. A., Marques, A. P., Ferreira, E. A. G., Assumpção, A., Lage, L. V., Casarotto, R. A., & Pereira, C. A. B. (2007). Effectiveness of muscle stretching exercises with and without laser therapy at tender points for patients with fibromyalgia. Clinical and Experimental Rheumatology, 25(3), 410-415.

This study evaluated the effectiveness of muscle stretching exercises combined with or without laser therapy at tender points in patients with fibromyalgia. The results demonstrated that the combination of stretching exercises and laser therapy led to significant improvements in pain, flexibility, and quality of life compared to stretching exercises alone.


The research papers discussed in this article provide strong evidence for the effectiveness of light therapy in managing fibromyalgia symptoms, including pain, fatigue, and stiffness. Through its ability to modulate pain signals, reduce inflammation, improve blood circulation, and promote muscle relaxation, light therapy offers a promising non-invasive, and drug-free treatment option for fibromyalgia management.

As our understanding of photobiomodulation and its potential applications in fibromyalgia treatment continues to grow, healthcare professionals and individuals with fibromyalgia can consider integrating light therapy into their treatment plans to support symptom management and improve the overall quality of life.

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